Enteric nervous system, gut-brain connection and related neurodevelopmental disorders
نویسندگان
چکیده
منابع مشابه
The enteric nervous system: a second brain.
Once dismissed as a simple collection of relay ganglia, the enteric nervous system is now recognized as a complex, integrative brain in its own right. Although we still are unable to relate complex behaviors such as gut motility and secretion to the activity of individual neurons, work in that area is proceeding briskly--and will lead to rapid advances in the management of functional bowel dise...
متن کاملThe gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems
The gut-brain axis (GBA) consists of bidirectional communication between the central and the enteric nervous system, linking emotional and cognitive centers of the brain with peripheral intestinal functions. Recent advances in research have described the importance of gut microbiota in influencing these interactions. This interaction between microbiota and GBA appears to be bidirectional, namel...
متن کاملHCV-Related Nervous System Disorders
Chronic infection with hepatitis C virus (HCV) is associated with a wide spectrum of extrahepatic manifestations, affecting different organ systems. Neurological complications occur in a large number of patients and range from peripheral neuropathy to cognitive impairment. Pathogenetic mechanisms responsible for nervous system dysfunction are mainly related to the upregulation of the host immun...
متن کاملBuilding a brain in the gut: development of the enteric nervous system.
The enteric nervous system (ENS), the intrinsic innervation of the gastrointestinal tract, is an essential component of the gut neuromusculature and controls many aspects of gut function, including coordinated muscular peristalsis. The ENS is entirely derived from neural crest cells (NCC) which undergo a number of key processes, including extensive migration into and along the gut, proliferatio...
متن کاملEnteric nervous system stem cells derived from human gut mucosa for the treatment of aganglionic gut disorders.
BACKGROUND & AIMS Enteric nervous system stem cells (ENSSCs) provide potential therapeutic tools to replenish absent ganglia in Hirschsprung's disease. Although full-thickness human postnatal gut tissue can be used to generate ENSSCs, reliance on its harvesting from surgical resection poses significant practical limitations. This study aimed to explore whether gut tissue obtained utilizing mini...
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ژورنال
عنوان ژورنال: Anatomy
سال: 2020
ISSN: 1308-8459
DOI: 10.2399/ana.20.008